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What does it mean to have CKD?

Chronic Kidney Disease (CKD) refers to a reduction in glomerular filtration rate (GFR) and the associated metabolic consequences linked to impaired renal function. Diabetes and hypertension are the two most common causes of CKD in the United States. The sequelae of kidney disease include complex hypertension, anemia, electrolyte disturbances, bone disease, and edema. The severity of CKD can be assessed through estimation of the GFR with a consensus-based staging system (see websites listed below). Patients with a sustained reduction in GFR are at risk of end-stage renal disease (ESRD) with a need for renal replacement therapy such as dialysis or transplantation. Patients with CKD are also at increased risk of other co-morbidities such as cardiovascular disease, which may lead to significant morbidity and mortality before the disease progresses to ESRD. Treatment with renin-angiotensin system (RAS) blockers such as angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) is encouraged in most CKD patients to help slow the rate at which patients lose renal function and reduce the risk of progression to ESRD. Please refer to the National Kidney Disease Education Program (NKDEP) and National Kidney Foundation website below for further information on CKD.

Last Updated - May 08 2017 15:25:50.

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